Drug

Amoxapine

As of the edition of 20 October 2026, Amoxapine is a small molecule: marketed, first approved in 1982 (US); acts on DRD1, DRD2 and DRD3 and 4 more; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1982
Kind
Small molecule
Brand name
Asendin
First approved
1 January 1982 (US)
Approvals on record
4 in 1 region
Holder of the most recent approval
Pfizer

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

4 company-target rows are on route B because of Amoxapine.

Targets

GeneProteinUniProt
DRD2Dopamine receptor D2P14416
DRD1Dopamine receptor D1P21728
DRD4Dopamine receptor D4P21917
DRD5Dopamine receptor D5P21918
SLC6A2Sodium-dependent noradrenaline transporterP23975
SLC6A4Sodium-dependent serotonin transporterP31645
DRD3Dopamine receptor D3P35462

Who has held its approvals

CompanyRoleYears
PfizerApplicant and Earlier holder