Target

SLC6A2

Sodium-dependent noradrenaline transporter

As of the edition of 20 October 2026, SLC6A2 (sodium-dependent noradrenaline transporter, UniProt P23975) has 56 drugs tested at it and 80 companies on the list, 9 on route A and 16 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P23975
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
37
Disease areas
Mental health; Nervous system; Chemically induced; Bones, joints and muscles; Nutrition and metabolism; Cancer; Urinary and reproductive; Lungs and airways
Registered trials of its drugs
1,627

Drugs at this target

StatusCount
Marketed36
Active3
Went quiet7
Stopped6
Withdrawn from market4
Total56
DrugStatusFurthest phaseUS protection
MethylphenidateMarketedPhase 4none listed
DuloxetineMarketedPhase 4none listed
BupropionMarketedPhase 4none listed
AtomoxetineMarketedPhase 4none listed
LisdexamfetamineMarketedPhase 4none listed
TapentadolMarketedPhase 4Ends 2027
PseudoephedrineMarketedPhase 4none listed
DextroamphetamineMarketedPhase 4none listed
AmphetamineMarketedPhase 4none listed
PhentermineMarketedPhase 4none listed
MilnacipranMarketedPhase 4none listed
DesipramineMarketedPhase 4none listed

12 of 56 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A9
Route B16
Engaged18
Undetermined37
Total on the list80
Three companies on route A or B, with the route only
CompanyRoute
NovartisRoute B
AbbVieRoute B
SanofiRoute B

The other 77 companies at SLC6A2

In the product

80 companies in all; 77 are not named here, and no score is.

See the 80 companies at SLC6A2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.