Drug

Amuvatinib

As of the edition of 20 October 2026, Amuvatinib is a small molecule: went quiet in 2012; acts on FLT3, KIT and MET and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2012
Kind
Small molecule
Registered trials
3, 0 stopped early
Disease areas
Cancer; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Amuvatinib.

Targets

GeneProteinUniProt
METHepatocyte growth factor receptorP08581
KITMast/stem cell growth factor receptor KitP10721
PDGFRAPlatelet-derived growth factor receptor alphaP16234
FLT3Receptor-type tyrosine-protein kinase FLT3P36888

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 21100
All trials3

Who ran its trials

CompanyRoleYears
OtsukaLead sponsor of trials2007 to now