Capmatinib
As of the edition of 20 October 2026, Capmatinib is a small molecule: marketed, first approved in 2020 (US); acts on MET; US protection ends in 2032.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2022
- Kind
- Small molecule
- Brand name
- Tabrecta
- First approved
- 6 May 2020 (US)
- Approvals on record
- 7 in 4 regions
- Holder of the most recent approval
- Novartis; 2 holders in all
- Registered trials
- 53, 18 stopped early
- Disease areas
- Cancer; Lungs and airways; Skin and connective tissue; Digestive system; Blood and lymph; Pregnancy and women's health
US protection
US protection ends in 2032.
The last listed US drug-substance patent ends in 2032. The application that gives this date is held by Novartis.
This is the US only, and it is not the date generics or biosimilars can enter.
The exact date and the listings behind it
In the product8 listings count towards this date. The exact date and each listing are in the product.
See the exact date and the 8 listings behind itRequest access. Nothing is shown until you do.
Companies that need a new molecule because of this drug
1 company on route B because of this drug.
Companies on route B for this drug
In the product1 company is on route B because of Capmatinib.
See the 1 company on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| MET | Hepatocyte growth factor receptor | P08581 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 4 | 3 | 0 | 0 |
| Phase 1 | 13 | 9 | 1 | 3 |
| Phase 2 | 30 | 10 | 5 | 13 |
| Phase 3 | 5 | 1 | 2 | 2 |
| Phase 4 | 1 | 1 | 0 | 0 |
| All trials | 53 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Novartis | Originator, Applicant and Lead sponsor of trials | 2020 to now |