Drug

Apolizumab

As of the edition of 20 October 2026, Apolizumab is an antibody: stopped in 2017; acts on HLA-DRB1, HLA-DRB3 and HLA-DRB4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2017
Kind
Antibody
Registered trials
6, 1 stopped early
Disease areas
Blood and lymph; Cancer; Immune system; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
HLA-DRB1HLA class II histocompatibility antigen, DRB1 beta chainP01911
HLA-DRB4HLA class II histocompatibility antigen, DR beta 4 chainP13762
HLA-DRB3HLA class II histocompatibility antigen, DR beta 3 chainP79483
HLA-DRB5HLA class II histocompatibility antigen, DR beta 5 chainQ30154

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13201
Phase 23200
All trials6

Who ran its trials

CompanyRoleYears
PDL BioPharmaLead sponsor of trials2000 to now