Target

HLA-DRB1

HLA class II histocompatibility antigen, DRB1 beta chain

As of the edition of 20 October 2026, HLA-DRB1 (HLA class II histocompatibility antigen, DRB1 beta chain, UniProt P01911) has 2 drugs tested at it and 1 company on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P01911
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
109
Disease areas
Immune system; Blood and lymph; Cancer; Infections; Nervous system
Registered trials of its drugs
7

Drugs at this target

StatusCount
Stopped2
Total2
DrugStatusFurthest phaseUS protection
ApolizumabStoppedPhase 2none listed
Plovamer acetateStoppedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Total on the list1
Three companies on route A or B, with the route only
CompanyRoute
Merck KGaARoute A

The other 0 companies at HLA-DRB1

In the product

1 company in all; 0 are not named here, and no score is.

See the 1 companies at HLA-DRB1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.