Drug

ASP-4058

As of the edition of 20 October 2026, ASP-4058 is a small molecule: went quiet in 2012; acts on S1PR1 and S1PR5.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2012
Kind
Small molecule
Registered trials
1, 0 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of ASP-4058.

Targets

GeneProteinUniProt
S1PR1Sphingosine 1-phosphate receptor 1P21453
S1PR5Sphingosine 1-phosphate receptor 5Q9H228

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
AstellasLead sponsor of trials2010 to now