Drug

Astegolimab

As of the edition of 20 October 2026, Astegolimab is an antibody: in active development; acts on IL1RAP and IL1RL1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2027
Kind
Antibody
Registered trials
9, 0 stopped early
Disease areas
Lungs and airways; Immune system; Inherited and neonatal; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
IL1RL1Interleukin-1 receptor-like 1Q01638
IL1RAPInterleukin-1 receptor accessory proteinQ9NPH3

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 25500
Phase 32020
All trials9

Who ran its trials

CompanyRoleYears
AmgenLead sponsor of trials2014 to now
RocheLead sponsor of trials2016 to now