Target

IL1RL1

Interleukin-1 receptor-like 1

As of the edition of 20 October 2026, IL1RL1 (interleukin-1 receptor-like 1, UniProt Q01638) has 2 drugs tested at it and 4 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q01638
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Lungs and airways; Immune system; Inherited and neonatal; Skin and connective tissue
Registered trials of its drugs
13

Drugs at this target

StatusCount
Active1
Went quiet1
Total2
DrugStatusFurthest phaseUS protection
AstegolimabActivePhase 3none listed
MelrilimabWent quietPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Undetermined2
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
GSKRoute A
Johnson & JohnsonRoute A

The other 2 companies at IL1RL1

In the product

4 companies in all; 2 are not named here, and no score is.

See the 4 companies at IL1RL1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.