Drug

AVN-944

As of the edition of 20 October 2026, AVN-944 is a small molecule: stopped in 2010; acts on IMPDH1 and IMPDH2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2010
Kind
Small molecule
Registered trials
3, 2 stopped early
Disease areas
Cancer; Blood and lymph; Digestive system; Heart and blood vessels; Hormones; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of AVN-944.

Targets

GeneProteinUniProt
IMPDH2Inosine-5'-monophosphate dehydrogenase 2P12268
IMPDH1Inosine-5'-monophosphate dehydrogenase 1P20839

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1001
Phase 11100
Phase 21001
All trials3

Who ran its trials

CompanyRoleYears
VertexLead sponsor of trials2006 to now