IMPDH2
Inosine-5'-monophosphate dehydrogenase 2
As of the edition of 20 October 2026, IMPDH2 (inosine-5'-monophosphate dehydrogenase 2, UniProt P12268) has 5 drugs tested at it and 10 companies on the list, 1 on route A and 2 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P12268
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 25
- Disease areas
- Immune system; Blood and lymph; Cancer; Heart and blood vessels; Urinary and reproductive; Pregnancy and women's health; Skin and connective tissue; Inherited and neonatal
- Registered trials of its drugs
- 871
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 3 |
| Active | 1 |
| Stopped | 1 |
| Total | 5 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Mycophenolate mofetil | Marketed | Phase 4 | none listed |
| Mycophenolic acid | Marketed | Phase 4 | none listed |
| Thioguanine | Marketed | Phase 4 | none listed |
| Mizoribine | Active | Phase 4 | none listed |
| AVN-944 | Stopped | Phase 2 | none listed |
5 of 5 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 1 |
| Route B | 2 |
| Engaged | 5 |
| Undetermined | 2 |
| Total on the list | 10 |
The other 7 companies at IMPDH2
In the product10 companies in all; 7 are not named here, and no score is.
See the 10 companies at IMPDH2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.