Drug

Ningetinib

As of the edition of 20 October 2026, Ningetinib is a small molecule: stopped in 2024; acts on AXL, FLT3 and MERTK and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Small molecule
Registered trials
7, 5 stopped early
Disease areas
Cancer; Lungs and airways; Blood and lymph

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

8 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

8 company-target rows are on route A because of Ningetinib.

Targets

GeneProteinUniProt
METHepatocyte growth factor receptorP08581
AXLTyrosine-protein kinase receptor UFOP30530
FLT3Receptor-type tyrosine-protein kinase FLT3P36888
MERTKTyrosine-protein kinase MerQ12866

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12101
Phase 25104
All trials7

Who ran its trials

CompanyRoleYears
Sunshine Lake PharmaLead sponsor of trials2014 to now
Jiangsu Alphamab BiopharmaceuticalsLead sponsor of trials2019 to now