Drug

Conatumumab

As of the edition of 20 October 2026, Conatumumab is an antibody: went quiet in 2020; acts on TNFRSF10B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Antibody
Registered trials
11, 2 stopped early
Disease areas
Cancer; Digestive system; Hormones; Lungs and airways; Blood and lymph; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 companies on route A because of this drug.

Companies on route A for this drug

In the product

3 companies are on route A because of Conatumumab.

Target

GeneProteinUniProt
TNFRSF10BTumor necrosis factor receptor superfamily member 10BO14763

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 29702
All trials11

Who ran its trials

CompanyRoleYears
ImmunitybioLead sponsor of trials2007 to now
AmgenLead sponsor of trials2007 to now
TetraLogic PharmaceuticalsLead sponsor of trials2013 to now