Drug

Emvododstat

As of the edition of 20 October 2026, Emvododstat is a small molecule: stopped in 2022; acts on DHODH.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2022
Kind
Small molecule
Registered trials
5, 4 stopped early
Disease areas
Cancer; Blood and lymph; Ear, nose and throat; Infections; Inherited and neonatal; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Emvododstat.

Target

GeneProteinUniProt
DHODHDihydroorotate dehydrogenaseQ02127

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13102
Phase 21001
Phase 31001
All trials5

Who ran its trials

CompanyRoleYears
PTC TherapeuticsLead sponsor of trials2007 to now