HMPL-453
As of the edition of 20 October 2026, HMPL-453 is a drug: in active development; acts on FGFR1, FGFR2 and FGFR3.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Active, 2025
- Kind
- Unknown
- Registered trials
- 8, 1 stopped early
- Disease areas
- Cancer; Digestive system
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Targets
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 4 | 3 | 0 | 1 |
| Phase 2 | 3 | 1 | 0 | 0 |
| Phase 3 | 1 | 0 | 1 | 0 |
| All trials | 8 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Hutchmed | Lead sponsor of trials | 2017 to now |