Drug

Ipafricept

As of the edition of 20 October 2026, Ipafricept is a protein: went quiet in 2017; acts on FZD8.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2017
Kind
Protein
Registered trials
4, 0 stopped early
Disease areas
Cancer; Digestive system; Hormones; Pregnancy and women's health; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Ipafricept.

Target

GeneProteinUniProt
FZD8Frizzled-8Q9H461

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 14400
All trials4

Who ran its trials

CompanyRoleYears
Mereo BioPharmaLead sponsor of trials2012 to now