FZD8
Frizzled-8
As of the edition of 20 October 2026, FZD8 (frizzled-8, UniProt Q9H461) has 2 drugs tested at it and 1 company on the list, 1 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- Q9H461
- How well studied
- Biology documented; no tool compounds or approved drug yet
- Where it sits in the cell
- In more than one place
- Solved structures
- 7
- Disease areas
- Cancer; Digestive system; Hormones; Pregnancy and women's health; Skin and connective tissue; Urinary and reproductive
- Registered trials of its drugs
- 8
Drugs at this target
| Status | Count |
|---|---|
| Went quiet | 2 |
| Total | 2 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Ipafricept | Went quiet | Phase 1 | none listed |
| Vantictumab | Went quiet | Phase 1 | none listed |
2 of 2 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 1 |
| Total on the list | 1 |
| Company | Route |
|---|---|
| Mereo BioPharma | Route A |
The other 0 companies at FZD8
In the product1 company in all; 0 are not named here, and no score is.
See the 1 companies at FZD8, ranked, with the facts behind eachRequest access. Nothing is shown until you do.