Drug

Istiratumab

As of the edition of 20 October 2026, Istiratumab is an antibody: went quiet in 2018; acts on ERBB3 and IGF1R.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Antibody
Registered trials
3, 1 stopped early
Disease areas
Cancer; Digestive system; Hormones; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Istiratumab.

Targets

GeneProteinUniProt
IGF1RInsulin-like growth factor 1 receptorP08069
ERBB3Receptor tyrosine-protein kinase erbB-3P21860

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12101
Phase 21100
All trials3

Who ran its trials

CompanyRoleYears
Merrimack PharmaceuticalsLead sponsor of trials2012 to now