Target

IGF1R

Insulin-like growth factor 1 receptor

As of the edition of 20 October 2026, IGF1R (insulin-like growth factor 1 receptor, UniProt P08069) has 21 drugs tested at it and 28 companies on the list, 13 on route A and 5 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P08069
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
46
Disease areas
Cancer; Hormones; Digestive system; Inherited and neonatal; Immune system; Lungs and airways; Eye; Skin and connective tissue
Registered trials of its drugs
230

Drugs at this target

StatusCount
Marketed5
Active2
Went quiet4
Stopped8
Status not established2
Total21
DrugStatusFurthest phaseUS protection
CixutumumabWent quietPhase 2none listed
GanitumabStoppedPhase 3none listed
TeprotumumabMarketedPhase 4Ends 2032
LinsitinibActivePhase 3none listed
FigitumumabStoppedPhase 3none listed
MecaserminMarketedPhase 3Ended 2017
DalotuzumabWent quietPhase 2none listed
VeligrotugMarketedPhase 4Ends 2038
BMS-754807StoppedPhase 2none listed
MHB018AActivePhase 3none listed
AXL-1717StoppedPhase 2none listed
RobatumumabStoppedPhase 2none listed

12 of 21 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A13
Route B5
Engaged4
Undetermined6
Total on the list28
Three companies on route A or B, with the route only
CompanyRoute
AmgenRoute B
PfizerRoute A
NovartisRoute A

The other 25 companies at IGF1R

In the product

28 companies in all; 25 are not named here, and no score is.

See the 28 companies at IGF1R, ranked, with the facts behind eachRequest access. Nothing is shown until you do.