Drug

KO-947

As of the edition of 20 October 2026, KO-947 is a small molecule: stopped in 2020; acts on MAPK1 and MAPK3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
1, 1 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of KO-947.

Targets

GeneProteinUniProt
MAPK3Mitogen-activated protein kinase 3P27361
MAPK1Mitogen-activated protein kinase 1P28482

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
All trials1

Who ran its trials

CompanyRoleYears
Kura OncologyLead sponsor of trials2017 to now