Drug

Liafensine

As of the edition of 20 October 2026, Liafensine is a small molecule: stopped in 2013; acts on SLC6A2, SLC6A3 and SLC6A4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2013
Kind
Small molecule
Registered trials
6, 1 stopped early
Disease areas
Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Liafensine.

Targets

GeneProteinUniProt
SLC6A2Sodium-dependent noradrenaline transporterP23975
SLC6A4Sodium-dependent serotonin transporterP31645
SLC6A3Sodium-dependent dopamine transporterQ01959

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 24301
All trials6

Who ran its trials

CompanyRoleYears
Bristol Myers SquibbLead sponsor of trials2009 to now
Denovo BiopharmaLead sponsor of trials2022 to now