Drug

Lorecivivint

As of the edition of 20 October 2026, Lorecivivint is a small molecule: stopped in 2023; acts on CLK2 and DYRK1A.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2023
Kind
Small molecule
Registered trials
12, 4 stopped early
Disease areas
Bones, joints and muscles

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Lorecivivint.

Targets

GeneProteinUniProt
CLK2Dual specificity protein kinase CLK2P49760
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1AQ13627

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13201
Phase 24301
Phase 35302
All trials12

Who ran its trials

CompanyRoleYears
Biosplice TherapeuticsLead sponsor of trials2014 to now