Target

CLK2

Dual specificity protein kinase CLK2

As of the edition of 20 October 2026, CLK2 (dual specificity protein kinase CLK2, UniProt P49760) has 2 drugs tested at it and 1 company on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P49760
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
6
Disease areas
Bones, joints and muscles; Injuries; Cancer; Digestive system; Hormones
Registered trials of its drugs
15

Drugs at this target

StatusCount
Went quiet1
Stopped1
Total2
DrugStatusFurthest phaseUS protection
LorecivivintStoppedPhase 3none listed
SM04755Went quietPhase 1none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Total on the list1
Three companies on route A or B, with the route only
CompanyRoute
Biosplice TherapeuticsRoute A

The other 0 companies at CLK2

In the product

1 company in all; 0 are not named here, and no score is.

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