Drug

Lorigerlimab

As of the edition of 20 October 2026, Lorigerlimab is an antibody: in active development; acts on CTLA4 and PDCD1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2026
Kind
Antibody
Registered trials
9, 2 stopped early
Disease areas
Cancer; Digestive system; Urinary and reproductive; Pregnancy and women's health; Skin and connective tissue; Hormones

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CTLA4Cytotoxic T-lymphocyte protein 4P16410
PDCD1Programmed cell death protein 1Q15116

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 27142
All trials9

Who ran its trials

CompanyRoleYears
MacroGenicsLead sponsor of trials2018 to now