Drug

LY-2874455

As of the edition of 20 October 2026, LY-2874455 is a small molecule: went quiet in 2020; acts on FGFR1, FGFR2 and FGFR3 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Cancer; Blood and lymph

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of LY-2874455.

Targets

GeneProteinUniProt
FGFR1Fibroblast growth factor receptor 1P11362
FGFR2Fibroblast growth factor receptor 2P21802
FGFR4Fibroblast growth factor receptor 4P22455
FGFR3Fibroblast growth factor receptor 3P22607

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
All trials2

Who ran its trials

CompanyRoleYears
Eli LillyLead sponsor of trials2010 to now