Drug

Marimastat

As of the edition of 20 October 2026, Marimastat is a small molecule: in active development; acts on MMP1, MMP2 and MMP3 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2027
Kind
Small molecule
Registered trials
4, 0 stopped early
Disease areas
Cancer; Blood and lymph; Chemically induced; Heart and blood vessels; Inherited and neonatal; Injuries

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
MMP1Interstitial collagenaseP03956
MMP272 kDa type IV collagenaseP08253
MMP3Stromelysin-1P08254
MMP7MatrilysinP09237
MMP9Matrix metalloproteinase-9P14780

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 21010
Phase 32200
All trials4

Who ran its trials

CompanyRoleYears
ILEX OncologyLead sponsor of trials1996 to now