Drug

MCLA-145

As of the edition of 20 October 2026, MCLA-145 is a drug known only by a code name: of no established status; acts on CD274 and TNFRSF9.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Status not established
Kind
Code name only
Registered trials
1, 0 stopped early
Disease areas
Blood and lymph; Cancer; Immune system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
TNFRSF9Tumor necrosis factor receptor superfamily member 9Q07011
CD274Programmed cell death 1 ligand 1Q9NZQ7

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
MerusLead sponsor of trials2019 to now