Drug

Melrilimab

As of the edition of 20 October 2026, Melrilimab is an antibody: went quiet in 2020; acts on IL1RL1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Antibody
Registered trials
4, 1 stopped early
Disease areas
Immune system; Lungs and airways; Inherited and neonatal; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of Melrilimab.

Target

GeneProteinUniProt
IL1RL1Interleukin-1 receptor-like 1Q01638

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 22101
All trials4

Who ran its trials

CompanyRoleYears
Johnson & JohnsonLead sponsor of trials2014 to now
GSKLead sponsor of trials2017 to now