Meprobamate
As of the edition of 20 October 2026, Meprobamate is a small molecule: marketed, first approved in 1982 (US); acts on GABRA1, GABRA2 and GABRA3 and 6 more; no US protection is listed.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 1982
- Kind
- Small molecule
- Brand name
- Equanil
- First approved
- 1 January 1982 (US)
- Approvals on record
- 37 in 1 region
- Holder of the most recent approval
- SUN Pharmaceutical Industries; 18 holders in all
- Withdrawn from market
- 1 January 1981 (in some regions)
US protection
No US protection is listed.
The FDA registers list no drug-substance patent or exclusivity that counts for this drug.
This is the US only.
Companies that need a new molecule because of this drug
3 company-target rows on route B because of this drug.
Companies on route B for this drug
In the product3 company-target rows are on route B because of Meprobamate.
See the 3 company-target rows on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Targets
| Gene | Protein | UniProt |
|---|---|---|
| GABRA1 | Gamma-aminobutyric acid receptor subunit alpha-1 | P14867 |
| GABRB1 | Gamma-aminobutyric acid receptor subunit beta-1 | P18505 |
| GABRB3 | Gamma-aminobutyric acid receptor subunit beta-3 | P28472 |
| GABRA5 | Gamma-aminobutyric acid receptor subunit alpha-5 | P31644 |
| GABRA3 | Gamma-aminobutyric acid receptor subunit alpha-3 | P34903 |
| GABRA2 | Gamma-aminobutyric acid receptor subunit alpha-2 | P47869 |
| GABRB2 | Gamma-aminobutyric acid receptor subunit beta-2 | P47870 |
| GABRA4 | Gamma-aminobutyric acid receptor subunit alpha-4 | P48169 |
| GABRA6 | Gamma-aminobutyric acid receptor subunit alpha-6 | Q16445 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Elkins Sinn | Acquired holder | 2003 to now |
| Stanlabs Pharmaceutical Co Sub Simpak | Acquired holder | 2003 to now |
| Teva | Acquired holder | 2003 to now |
| Medpointe Pharmaceuticals Medpointe Healthcare | Acquired holder | 2003 to now |
| Sandoz | Acquired holder | 2005 to now |
| Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals | Acquired holder | 2009 to now |
| Chartwell Molecular | Acquired holder | 2022 to now |
| Amneal Pharmaceuticals | Later holder | |
| Bausch Health | Later holder | |
| Everylife | Later holder | |
| Halsey Drug | Later holder | |
| Heather Drug | Later holder | |
| Hikma Pharmaceuticals | Later holder | |
| Lannett | Later holder | |
| Mallard | Later holder | |
| Mk | Later holder | |
| Pfizer | Later holder | |
| Private Formulations | Later holder | |
| Solvay Pharmaceuticals | Later holder | |
| Teva | Later holder |