GABRA2
Gamma-aminobutyric acid receptor subunit alpha-2
As of the edition of 20 October 2026, GABRA2 (gamma-aminobutyric acid receptor subunit alpha-2, UniProt P47869) has 29 drugs tested at it and 2 companies on the list, 1 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P47869
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 15
- Disease areas
- Nervous system; Mental health; Cancer; Lungs and airways; Infections; Digestive system; Urinary and reproductive; Immune system
- Registered trials of its drugs
- 1,257
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 23 |
| Went quiet | 3 |
| Stopped | 3 |
| Total | 29 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Midazolam | Marketed | Phase 4 | none listed |
| Remimazolam | Marketed | Phase 4 | none listed |
| Lorazepam | Marketed | Phase 4 | none listed |
| Alprazolam | Marketed | Phase 4 | none listed |
| Eszopiclone | Marketed | Phase 4 | none listed |
| Diazepam | Marketed | Phase 4 | none listed |
| Clonazepam | Marketed | Phase 4 | none listed |
| Flumazenil | Marketed | Phase 4 | none listed |
| Zopiclone | Marketed | Phase 4 | none listed |
| Clobazam | Marketed | Phase 4 | none listed |
| AZD7325 | Stopped | Phase 2 | none listed |
| Padsevonil | Stopped | Phase 3 | none listed |
12 of 29 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 1 |
| Undetermined | 1 |
| Total on the list | 2 |
| Company | Route |
|---|---|
| AstraZeneca | Route A |
The other 1 company at GABRA2
In the product2 companies in all; 1 is not named here, and no score is.
See the 2 companies at GABRA2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.