Drug

NS-2359

As of the edition of 20 October 2026, NS-2359 is a small molecule: went quiet in 2020; acts on SLC6A2, SLC6A3 and SLC6A4.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Small molecule
Registered trials
7, 0 stopped early
Disease areas
Mental health; Chemically induced

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B and 3 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of NS-2359.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of NS-2359.

Targets

GeneProteinUniProt
SLC6A2Sodium-dependent noradrenaline transporterP23975
SLC6A4Sodium-dependent serotonin transporterP31645
SLC6A3Sodium-dependent dopamine transporterQ01959

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13200
Phase 24400
All trials7

Who ran its trials

CompanyRoleYears
NeuroSearch A/SLead sponsor of trials2003 to now
GSKLead sponsor of trials2006 to now