Drug

ORM-12741

As of the edition of 20 October 2026, ORM-12741 is a small molecule: went quiet in 2018; acts on ADRA2C.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Small molecule
Registered trials
11, 0 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of ORM-12741.

Target

GeneProteinUniProt
ADRA2CAlpha-2C adrenergic receptorP18825

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 19900
Phase 22200
All trials11

Who ran its trials

CompanyRoleYears
OrionLead sponsor of trials2008 to now