Drug

Pactimibe

As of the edition of 20 October 2026, Pactimibe is a small molecule: stopped in 2006; acts on SOAT1 and SOAT2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2006
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Pactimibe.

Targets

GeneProteinUniProt
SOAT2Sterol O-acyltransferase 2O75908
SOAT1Sterol O-acyltransferase 1P35610

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22200
Phase 31001
All trials3

Who ran its trials

CompanyRoleYears
Daiichi SankyoLead sponsor of trials2002 to now