Target

SOAT1

Sterol O-acyltransferase 1

As of the edition of 20 October 2026, SOAT1 (sterol O-acyltransferase 1, UniProt P35610) has 3 drugs tested at it and 3 companies on the list, 3 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P35610
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
5
Disease areas
Hormones; Heart and blood vessels; Nutrition and metabolism; Inherited and neonatal; Pregnancy and women's health; Urinary and reproductive; Cancer
Registered trials of its drugs
8

Drugs at this target

StatusCount
Stopped2
Withdrawn from market1
Total3
DrugStatusFurthest phaseUS protection
NevanimibeStoppedPhase 2none listed
PactimibeStoppedPhase 3none listed
BenfluorexWithdrawn from marketPhase 2none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
Millendo TherapeuticsRoute A
Millendo TherapeuticsRoute A
Daiichi SankyoRoute A

The other 0 companies at SOAT1

In the product

3 companies in all; 0 are not named here, and no score is.

See the 3 companies at SOAT1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.