Patidegib
As of the edition of 20 October 2026, Patidegib is a small molecule: stopped in 2021; acts on SMO.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Stopped, 2021
- Kind
- Small molecule
- Registered trials
- 11, 2 stopped early
- Disease areas
- Cancer; Bones, joints and muscles; Inherited and neonatal; Mouth and teeth; Blood and lymph; Digestive system
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of Patidegib.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| SMO | Protein smoothened | Q99835 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 1 | 1 | 0 | 0 |
| Phase 1 | 3 | 3 | 0 | 0 |
| Phase 2 | 4 | 3 | 0 | 1 |
| Phase 3 | 3 | 2 | 0 | 1 |
| All trials | 11 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Infinity Pharmaceuticals | Lead sponsor of trials | 2008 to now |
| PellePharm | Lead sponsor of trials | 2016 to now |
| Sol-Gel Technologies | Lead sponsor of trials | 2019 to now |