Taladegib
As of the edition of 20 October 2026, Taladegib is a small molecule: in active development; acts on SMO.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Active, 2026
- Kind
- Small molecule
- Registered trials
- 13, 4 stopped early
- Disease areas
- Cancer; Lungs and airways; Digestive system; Skin and connective tissue; Ear, nose and throat; Eye
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of Taladegib.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| SMO | Protein smoothened | Q99835 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 8 | 5 | 1 | 2 |
| Phase 2 | 5 | 2 | 1 | 2 |
| All trials | 13 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Eli Lilly | Lead sponsor of trials | 2010 to now |
| Endeavor Biomedicines | Lead sponsor of trials | 2021 to now |