Drug

Piritrexim

As of the edition of 20 October 2026, Piritrexim is a small molecule: went quiet in 2004; acts on DHFR.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2004
Kind
Small molecule
Registered trials
1, 0 stopped early
Disease areas
Cancer; Pregnancy and women's health; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Target

GeneProteinUniProt
DHFRDihydrofolate reductaseP00374

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21100
All trials1