Drug

PL-225B

As of the edition of 20 October 2026, PL-225B is a drug: stopped in 2014; acts on IGF1R.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2014
Kind
Unknown
Registered trials
1, 0 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of PL-225B.

Target

GeneProteinUniProt
IGF1RInsulin-like growth factor 1 receptorP08069

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11000
All trials1

Who ran its trials

CompanyRoleYears
Piramal EnterprisesLead sponsor of trials2012 to now