Drug

Rislenemdaz

As of the edition of 20 October 2026, Rislenemdaz is a small molecule: went quiet in 2016; acts on GRIN1 and GRIN2B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2016
Kind
Small molecule
Registered trials
4, 0 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Rislenemdaz.

Targets

GeneProteinUniProt
GRIN1Glutamate receptor ionotropic, NMDA 1Q05586
GRIN2BGlutamate receptor ionotropic, NMDA 2BQ13224

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 22200
All trials4

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2007 to now
Avalo TherapeuticsLead sponsor of trials2013 to now