Drug

Rosmantuzumab

As of the edition of 20 October 2026, Rosmantuzumab is an antibody: went quiet in 2018; acts on LGR4 and RSPO3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Antibody
Registered trials
1, 0 stopped early
Disease areas
Cancer; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
LGR4Leucine-rich repeat-containing G protein-coupled receptor 4Q9BXB1
RSPO3R-spondin-3Q9BXY4

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
Mereo BioPharmaLead sponsor of trials2015 to now