Drug

Sarizotan

As of the edition of 20 October 2026, Sarizotan is a small molecule: stopped in 2020; acts on DRD2, DRD3 and DRD4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
6, 2 stopped early
Disease areas
Nervous system; Inherited and neonatal; Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

8 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

8 company-target rows are on route A because of Sarizotan.

Targets

GeneProteinUniProt
HTR1A5-hydroxytryptamine receptor 1AP08908
DRD2Dopamine receptor D2P14416
DRD4Dopamine receptor D4P21917
DRD3Dopamine receptor D3P35462

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1001
Phase 22200
Phase 33201
All trials6

Who ran its trials

CompanyRoleYears
Merck KGaALead sponsor of trials2002 to now
Newron PharmaceuticalsLead sponsor of trials2016 to now