Drug

Simenepag isopropyl

As of the edition of 20 October 2026, Simenepag isopropyl is a small molecule: went quiet in 2011; acts on PTGER2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2011
Kind
Small molecule
Registered trials
3, 0 stopped early
Disease areas
Eye

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Simenepag isopropyl.

Target

GeneProteinUniProt
PTGER2Prostaglandin E2 receptor EP2 subtypeP43116

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 23300
All trials3

Who ran its trials

CompanyRoleYears
AbbVieLead sponsor of trials2009 to now