Drug

Tamnorzatinib

As of the edition of 20 October 2026, Tamnorzatinib is a small molecule: in active development; acts on AXL and MERTK.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2027
Kind
Small molecule
Registered trials
4, 1 stopped early
Disease areas
Cancer; Blood and lymph; Digestive system; Hormones; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
AXLTyrosine-protein kinase receptor UFOP30530
MERTKTyrosine-protein kinase MerQ12866

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13210
Phase 21001
All trials4

Who ran its trials

CompanyRoleYears
Ono PharmaceuticalLead sponsor of trials2017 to now