Drug

UCN-01

As of the edition of 20 October 2026, UCN-01 is a small molecule: stopped in 2013; acts on CDK2, CDK4 and CDK6 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2013
Kind
Small molecule
Registered trials
22, 3 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Hormones; Urinary and reproductive; Pregnancy and women's health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CHEK1Serine/threonine-protein kinase Chk1O14757
PDPK13-phosphoinositide-dependent protein kinase 1O15530
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941
CDK6Cyclin-dependent kinase 6Q00534

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 1151401
Phase 27402
All trials22