ABCB1
ATP-dependent translocase ABCB1
As of the edition of 20 October 2026, ABCB1 (ATP-dependent translocase ABCB1, UniProt P08183) has 5 drugs tested at it and 6 companies on the list, 4 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P08183
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 24
- Disease areas
- Cancer; Blood and lymph; Skin and connective tissue; Pregnancy and women's health; Urinary and reproductive; Hormones; Inherited and neonatal; Lungs and airways
- Registered trials of its drugs
- 46
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Went quiet | 2 |
| Stopped | 2 |
| Total | 5 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Encequidar | Active | Phase 3 | none listed |
| Valspodar | Went quiet | Phase 3 | none listed |
| Tariquidar | Stopped | Phase 3 | none listed |
| Zosuquidar | Went quiet | Phase 3 | none listed |
| Biricodar | Stopped | Phase 2 | none listed |
5 of 5 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 4 |
| Engaged | 2 |
| Total on the list | 6 |
| Company | Route |
|---|---|
| Kanisa Pharmaceuticals | Route A |
| Athenex | Route A |
| Qlt | Route A |
The other 3 companies at ABCB1
In the product6 companies in all; 3 are not named here, and no score is.
See the 6 companies at ABCB1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.