Target

TUBB

Tubulin beta chain

As of the edition of 20 October 2026, TUBB (tubulin beta chain, UniProt P07437) has 46 drugs tested at it and 16 companies on the list, 5 on route A and 5 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P07437
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
21
Disease areas
Cancer; Skin and connective tissue; Urinary and reproductive; Lungs and airways; Digestive system; Blood and lymph; Immune system; Pregnancy and women's health
Registered trials of its drugs
7,727

Drugs at this target

StatusCount
Marketed17
Active5
Went quiet16
Stopped7
Status not established1
Total46
DrugStatusFurthest phaseUS protection
PaclitaxelMarketedPhase 4none listed
Docetaxel anhydrousMarketedPhase 4none listed
VincristineMarketedPhase 4none listed
VinorelbineMarketedPhase 4none listed
ColchicineMarketedPhase 4none listed
Brentuximab vedotinMarketedPhase 4Ends 2029
EribulinMarketedPhase 4Ended 2026
VinblastineMarketedPhase 4none listed
Trastuzumab emtansineMarketedPhase 4Ended 2025
CabazitaxelMarketedPhase 4Ended 2025
IxabepiloneMarketedPhase 3none listed
Polatuzumab vedotinMarketedPhase 3Ends 2031

12 of 46 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A5
Route B5
Engaged6
Total on the list16
Three companies on route A or B, with the route only
CompanyRoute
EisaiRoute B
AbbVieRoute B
GSKRoute B

The other 13 companies at TUBB

In the product

16 companies in all; 13 are not named here, and no score is.

See the 16 companies at TUBB, ranked, with the facts behind eachRequest access. Nothing is shown until you do.