Target

ALDH2

Aldehyde dehydrogenase, mitochondrial

As of the edition of 20 October 2026, ALDH2 (aldehyde dehydrogenase, mitochondrial, UniProt P05091) has 2 drugs tested at it and 3 companies on the list, 1 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P05091
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
29
Disease areas
Cancer; Chemically induced; Mental health; Infections; Immune system; Skin and connective tissue; Urinary and reproductive; Lungs and airways
Registered trials of its drugs
53

Drugs at this target

StatusCount
Marketed1
Went quiet1
Total2
DrugStatusFurthest phaseUS protection
DisulfiramMarketedPhase 4none listed
ANS-6637Went quietPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B1
Undetermined1
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
StallergenesRoute B
Amygdala NeurosciencesRoute A

The other 1 company at ALDH2

In the product

3 companies in all; 1 is not named here, and no score is.

See the 3 companies at ALDH2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.