Target

AOC3

Amine oxidase [copper-containing] 3

As of the edition of 20 October 2026, AOC3 (amine oxidase [copper-containing] 3, UniProt Q16853) has 3 drugs tested at it and 3 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q16853
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
11
Disease areas
Digestive system; Bones, joints and muscles; Eye; Heart and blood vessels; Hormones; Immune system; Pregnancy and women's health; Skin and connective tissue
Registered trials of its drugs
14

Drugs at this target

StatusCount
Went quiet2
Status not established1
Total3
DrugStatusFurthest phaseUS protection
BI 1467335Went quietPhase 2none listed
TimolumabWent quietPhase 2none listed
TT-01025-CLStatus not establishedPhase 1none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Undetermined1
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
Boehringer IngelheimRoute A
Biotie TherapiesRoute A

The other 1 company at AOC3

In the product

3 companies in all; 1 is not named here, and no score is.

See the 3 companies at AOC3, ranked, with the facts behind eachRequest access. Nothing is shown until you do.