APEX1
DNA repair nuclease/redox regulator APEX1
As of the edition of 20 October 2026, APEX1 (DNA repair nuclease/redox regulator APEX1, UniProt P27695) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P27695
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 68
- Disease areas
- Cancer; Eye; Heart and blood vessels; Hormones; Nutrition and metabolism
- Registered trials of its drugs
- 2
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| APX-3330 | Active | Phase 2 | none listed |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Engaged | 2 |
| Total on the list | 2 |