APLNR
Apelin receptor
As of the edition of 20 October 2026, APLNR (apelin receptor, UniProt P35414) has 4 drugs tested at it and 3 companies on the list, 3 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P35414
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 39
- Disease areas
- Heart and blood vessels; Nutrition and metabolism; Hormones; Lungs and airways; Nervous system; Pregnancy and women's health; Urinary and reproductive
- Registered trials of its drugs
- 17
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Went quiet | 1 |
| Stopped | 2 |
| Total | 4 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Apelin | Active | Phase 2 | none listed |
| BMS-986224 | Went quiet | Phase 1 | none listed |
| AMG 986 | Stopped | Phase 1 | none listed |
| Azelaprag | Stopped | Phase 2 | none listed |
4 of 4 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 3 |
| Total on the list | 3 |
| Company | Route |
|---|---|
| BioAge | Route A |
| Amgen | Route A |
| Bristol Myers Squibb | Route A |
The other 0 companies at APLNR
In the product3 companies in all; 0 are not named here, and no score is.
See the 3 companies at APLNR, ranked, with the facts behind eachRequest access. Nothing is shown until you do.